Precancerous lesions of the cervix and associated factors among women of east gojjam, northwest Ethiopia, 2020

Title : Precancerous lesions of the cervix and associated factors among women of east gojjam, northwest Ethiopia, 2020

Abstract:

Background: Cervical cancer is the commonest cancer of women’s reproductive system, and is caused by a progression of precancerous lesions of the cervix. Studies on the prevalence and associated factors of precancerous lesions of the cervix are very limited in Ethiopia, particularly in the study area.
Objective: This study aimed to assess precancerous lesions of the cervix and associated factors among women of East Gojjam, northwest Ethiopia in 2020.
Methods: A facility-based cross-sectional study was conducted on 340 cervical cancer– screened women in three hospitals of East Gojjam from February to April 2020. Data were collected by six BSc-qualified nurses who were working in the selected hospitals. EpiData Manager and SPSS 26 were used for data management and analysis. After the data had been clean, descriptive analysis was done and multivariate logistic regression used to identify predictors of precancerous lesions of the cervix. Statistical significance was taken to be P<0.05.
Results: Of the 340 recruited women, 15.3% (95% CI 11.83%–19.54%) had precancerous cervical lesions. Mean age was 37.11±9.3 years. Age 46–55 (AOR 3.8, 95% CI 1.21–12.47) years, age 56–65 (AOR 12.26, 95% CI 3.18–47.18) years, residing rurally (AOR 2.04, 95% CI 1.12–3.7), prolonged use of oral contraceptive pills (AOR 9.11, 95% CI 1.14–72.8), history of sexual transmitted infection (STI; AOR 3.40, 95% CI 1.32–8.78), HIV-positive status (AOR 4.89, 95% CI 1.54–15.49), and number of lifetime sexual partners (AOR 9.87, 95% CI 1.38– 70.4) were important factors associated with precancerous lesions of the cervix.
Conclusion: We found relatively high prevalence of precancerous cervical lesions. Age, rural residence, prolonged use of oral contraceptives, STI, multiple sexual partners, and being HIV-positive were important factors associated with precancerous cervical lesions. Women aged >46 years, with a history of STI, being HIV infected, and with a history of multiple sexual partners should be encouraged to get screened for cervical cancer.
Keywords: Visual Inspection After Acetic Acid, Precancerous Lesions of Cervix, Cervical Cancer, East Gojam Zone.

Biography:

Molla Taye is associate professor of clinical anatomy at the University of Gondar, Ethiopia. He received his Ph.D. in anatomy at Addis Ababa University, Ethiopia in 2017. He obtained an MSc degree from the University of Gondar, Ethiopia in 2010, and his BSc degree in Public Health from the University of Gondar, Ethiopia in 2000. He had worked as a registered nursing professional for 7 years. He joined the University of Gondar as a lecturer in 2010. He has been teaching medical and health science undergraduate and postgraduate students, as well as supervising postgraduate student’s research works/thesis/projects. He has been engaged in research activities and produced scientific publications in peer reviewed journals. His research interests include birth defects/congenital anomalies, Clinical research (medicine and health sciences) and cancer.